منابع مشابه
Altered Proteins in the Aging Brain
We assessed the prevalence of common altered brain proteins in 296 cognitively unimpaired subjects ranging from age 50 to 102 years. The incidence and the stage of hyperphosphorylated-τ (HPτ), β-amyloid, α-synuclein (αS), and transactive response DNA (TDP) binding protein 43 (TDP43)-immunoreactivity (-IR) increased with age. HPτ-IR was observed in 98% of the subjects; the locus coeruleus was so...
متن کاملAn evolutionary approach to myelin proteins and myelin-forming cells in the vertebrate brain.
12. Hunge, M. H., Hunge, K. P., Carey, L). J.? Cornbrooks, C. J,? Eldridge, C. F., Williams, A. K. & Wood, 1’. M. (1 983) in Developing And Regenerating Vertebrate Nervous Systems (Coates, P. W., Markwald, K. K. & Kenny, A. D.? eds.), pp. 71-105, I,iss, New York Sobue, G., Yasuda, T., Mitsuma, T. & Pleasure, I). (1986) Neurosci. Lett. 72,253-257 Morgan, I,., Jessen, K. R. & Mirsky, K. (1991) J....
متن کاملThe Aging Human Brain
The human brain weighs on average about three pounds, consists of 200 billion cells. Surprisingly, there are only two categories of brain cells, neurons and glia, but more than 50 different cellular subtypes. Nerve cells or neurons are specialized cells that are electrically excitable, and processes and transmit information to other neurons and cells through electrochemical signaling v...
متن کاملbioinformatics approach for pattern of myelin-specific proteins and related human disorders
conclusions the growth rate of information in bioinformatics databases could facilitate studies of live organisms prior to observation studies. two different protein classes could be causative agents of one disease. however, two related diseases from one disease group could consist of different protein classes. future research in the field of proteomics could allow modern insight to reshuffling...
متن کاملDiffusion changes in the aging human brain.
BACKGROUND AND PURPOSE Quantifying changes in the human brain that occur as part of normal aging may help in the diagnosis of diseases that affect the elderly and that cause structural changes in the brain. We sought to assess diffusion changes that are inherently related to brain structure during aging. METHODS MR scans were obtained from 11 healthy volunteers and 27 patients (ages 26 to 86 ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular and Chemical Neuropathology
سال: 1991
ISSN: 1044-7393
DOI: 10.1007/bf03160993